ELISA DNMT3A Antibody, Biotin

Quantity :50µg Clone Number: Aliases:DNA (cytosine 5) methyltransferase 3 alpha antibody; DNA (cytosine 5) methyltransferase 3A antibody; DNA (cytosine-5)-methyltransferase 3A antibody; DNA cytosine methyltransferase 3A2 antibody; DNA methyltransferase 3 alpha antibody; DNA methyltransferase 3a antibody; DNA methyltransferase HsaIIIA antibody; DNA MTase HsaIIIA antibody; DNM3A_ antibody; DNMT 3a antibody; DNMT antibody; Dnmt3a antibody; DNMT3A2 antibody; M.HsaIIIA antibody; MCMT antibody; OTTHUMP00000201149 antibody; TBRS antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y6K1 Immunogen:Recombinant DNA (cytosine-5)-methyltransferase 3A protein (680-902AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription throµgh the recruitment of HDAC activity Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DNMT3A Research Areas:Epigenetics and Nuclear Signaling