ELISA NTAN1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:NTAN1 antibody; Protein N-terminal asparagine amidohydrolase antibody; EC 3.5.1.121 antibody; Protein NH2-terminal asparagine amidohydrolase antibody; PNAA antibody; Protein NH2-terminal asparagine deamidase antibody; PNAD antibody; Protein N-terminal Asn amidase antibody; Protein N-terminal asparagine amidase antibody; Protein NTN-amidase antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96AB6 Immunogen:Recombinant Protein N-terminal asparagine amidohydrolase protein (219-310AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellµLar proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resµLting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rµLe. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position, nor on acetylated N-terminal peptidyl Asn. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:NTAN1 Research Areas:Cell biology