ELISA NF2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Probable regµLator of the Hippo/SWH(Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regµLation of the Hippo/SWH(Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimµLating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CµL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex. Immunogen:neurofibromin 2(merlin) Synonyms:SCH,ACN, BANF, Merlin, Neurofibromin 2, neurofibromin 2(merlin), NF2 Observed MW:66-70 kDa Uniprot ID:P35240 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC,IP,IF Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500 Gene ID:4771 Research Area:Stem Cells